In the 2021 season Letterman Lanigan Racing again expanded to three cars, with Graham Rahal and Takuma Sato driving two full-time entries while several drivers would drive a third car on a part-time basis. Santino Ferrucci took the seat in the third entry, #45 baked by HyVee, a chain of supermarkets in the Midwestern and Southern United States, in five races. He scored four top-10 finishes, including 6th in the Indy 500 and 6th in the first race at Detroit, and ended the season in 24th position with 146 points.
| Season | Series | Event |
| 2021 | IndyCar Series | |
| Driver | No. | Entrant |
| Santino Ferrucci | 45 | Rahal Letterman Lanigan Racing |
| Chassis | Engine | Car Name |
| Dallara DW12 (IR18) | Honda | HyVee |
| Scale | Manufacturer | Collection |
| 1:64 | Greenlight | |
| Cat. No. | Quality | Rarity |
| 11521 | 
| 
|
formula143 